MyHeritage
Best new genealogy-focused WGS entrant. MyHeritage's October 2025 move to low-pass whole genome sequencing — via an Ultima Genomics wafer partnership and Gene by Gene's Houston lab — is the single biggest shake-up of the consumer-DNA market in 2025. It is not a 30× health lab and we do not score it against mainstream-health peers; it is the right answer for family-history research at a price no other WGS provider approaches. First major consumer-DNA brand to migrate to whole-genome sequencing (Oct 2025). Our review covers all eight dimensions we test — from coverage depthcoverageHow many times, on average, each base is read. 30× is the consumer standard; 100× is used for hard-to-call variants and some cancer assays; 1× (low-pass) is suitable for genealogy but not for clinical variant calls. to clinical reporting quality — based on kits purchased with reader-supported funds, timed turnarounds across six orders, and an independent check of raw read filesFASTQRaw sequencing read file. The unprocessed output of the sequencer..
- ＋Whole-genome coverage at a $89 genealogy-kit price — first time any mainstream brand has crossed that line
- ＋Ultima Genomics wafer-based LP-WGS is a real technological breakthrough, not a marketing word game
- ＋All existing MyHeritage DNA-matching features carry forward against the same database
- ＋CRAM-format raw data will be downloadable once MyHeritage ships the feature
- —This is LP-WGS (~1× coverage), not 30× — it is NOT a substitute for a health-focused WGS lab
- —Variant-calling for rare or clinical findings is not supported by the sequencing depth
- —Raw data download is promised but not yet available at time of writing
Pricing & coverage tiers
| Tier | Coverage | Price | Best for |
|---|---|---|---|
| MyHeritage DNA (LP-WGS) | ≈1× LP | $89 | — |
- Ethnicity estimate across ~2,100 geographic regions
- DNA matching with the broader MyHeritage database
- Family-tree integration
- Raw LP-WGS in CRAM format (download support expected in 2026)
Consumer-genealogy standard; data stored under MyHeritage's existing privacy framework
The MyHeritage dossier, based on public information.
Template narrative · pending independent testing
MyHeritage sits in the consumer whole genome sequencingWGSWhole Genome Sequencing — reading (nearly) all 3 billion base pairs of your DNA, as opposed to genotyping arrays which sample ~600,000 known positions. market at a price point of $89. Sequencing runs on low-pass whole genome sequencing (lp-wgs) via ultima genomics wafer technology; processed at gene by gene (houston, tx). Company's public turnaround claim: 6–10 weeks. This section renders a structured summary from public information until our reader-supported testing cycle publishes.
Raw files — BAMBAMAligned reads mapped to a reference genome. The typical intermediate file., FASTQFASTQRaw sequencing read file. The unprocessed output of the sequencer., VCFVCFVariant Call Format — the compact list of positions where your genome differs from the reference. — are not offered by this provider. Best new genealogy-focused WGS entrant. Our editorial verdict at a glance: Best new genealogy-focused WGS entrant. MyHeritage's October 2025 move to low-pass whole genome sequencing — via an Ultima Genomics wafer partnership and Gene by Gene's Houston lab — is the single biggest shake-up of the consumer-DNA market in 2025. It is not a 30× health lab and we do not score it against mainstream-health peers; it is the right answer for family-history research at a price no other WGS provider approaches.
The documented weak spots are this is lp-wgs (~1× coverage), not 30× — it is not a substitute for a health-focused wgs lab, and raw data download is promised but not yet available at time of writing. Neither is necessarily a deal-breaker, but both are worth weighing before you click buy.
Editors can replace this template with a full narrative in the Payload admin: Collections → Companies → MyHeritage → Full review (company detail page).