Nebula Genomics is gone. DNA Complete is the successor. Here's what Nebula subscribers should do.
On February 5, 2025, Nebula Genomics — the consumer whole-genome-sequencing company co-founded in 2016 by Harvard geneticist George Church and acquired by ProPhase Labs in 2021 for approximately $14.6M — discontinued its direct-to-consumer service. Account access, new kit orders, and the ongoing "Weekly Updates" research reports that had been the product's most distinctive feature all stopped. By published estimates, around 200,000 Nebula subscribers were affected.
What hadn't been widely understood at the time: ProPhase had already launched a successor product three months earlier. DNA Complete, at dnacomplete.com, opened for business in November 2024. Same parent company, same sequencing infrastructure, a re-bundled consumer reporting suite, and explicit continuity language on the website ("DNA Complete is powered by Nebula Genomics, a division of ProPhase Labs"). The nebula.org domain now redirects to DNA Complete. For ProPhase, February 2025 was less a shutdown than a rebrand.
For Nebula customers, it's still a downgrade. The privacy-first pitch that made the original Nebula distinctive — blockchain-brokered access controls, user-held keys, anonymized research participation on your own terms — did not carry forward to DNA Complete. The new product is organized around consumer health, ancestry, and traits, through a more conventional storage and access model. If you bought Nebula specifically for the privacy posture, DNA Complete is not the replacement it appears to be.
Three things matter right now.
First: your raw data is probably still accessible if you downloaded it before February 2025. Nebula was one of the more generous providers for raw data — FASTQ, BAM, and VCF files were all available to paying subscribers. Those files work anywhere. You can upload the VCF into Sequencing.com's marketplace (many of their apps accept third-party raw data), feed it into Genomapp, run it through SelfDecode, or keep it archived. A BAM is ~40GB; a VCF is a few hundred MB. Store it somewhere you control.
Second: if you did not download, the picture is worse. ProPhase has not publicly committed to a long retention window for the old Nebula infrastructure, and we are unaware of public documentation on whether existing Nebula data migrates cleanly into DNA Complete accounts. Worth writing to them directly.
Third: for net-new buyers considering DNA Complete on name recognition, the honest framing is that it's a respectable mainstream-health WGS product from a known operator, with <18 months of consumer track record under this brand. It's on our leaderboard in the Recommended tier. It's not the privacy-first pick Nebula was, and shopping around is healthy. Nucleus (best UX), Sequencing.com (best value, widest turnaround menu), SelfDecode (best ACMG reporting), and Veritas (clinical-grade) are all within a reasonable price delta.
Nebula's departure is also worth reading as a signal about the market. The consumer WGS category has quietly consolidated in 2025 — Nebula rebranded under its parent, MyHeritage moved to LP-WGS via Ultima, and at least three new mainstream-health entrants opened the door. The next two to three years are likely to bring more consolidation, more clinical-gating, and possibly another round of shutdowns. Download your raw data. Every time.